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KMID : 0379119860140010049
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Korean Journal of Mycology
1986 Volume.14 No. 1 p.49 ~ p.59
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Studies on Safety of Ganoderma lucidum
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Abstract
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To examine safety of Ganoderma lucidum, it was extracted with hot water (Fraction A). After the extract was dialyzed and freeze-dried, a polysaccharide fraction (Fraction B) was obtained and examined for acute and subacute toxicity. In the acute toxicity tests of Fr. A and Fr. B on mice, both agents did not show any serious and lethal effects. The results showed that 50% lethal doses were higher than 5,000 ㎎/㎏. The experiments of oral administration of Fr. A (5,000 ㎎/㎏) to mice for 30 days showed that there were no changes in body weight, hematological features and organ weight.
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